Conduct research on ADC conjugation processes (e.g., cysteine conjugation, enzyme-catalyzed site-specific conjugation).
Perform stability analysis of ADC samples, with familiarity in common analytical methods such as SEC-HPLC, HIC, RP-HPLC, UV-Vis, and MS.
Track global ADC drug development progress, analyze competitor technology routes (linker, Payload, conjugation technology), investigate and design novel Payloads (e.g., novel toxins, immunomodulators), and prepare technical evaluation reports to support pipeline strategy.
Independently address technical challenges in process development based on literature and industry reports, design experimental plans, and conduct verification.
PhD degree or Master’s degree with over 5 years of relevant experience in Medicinal Chemistry, Molecular Biology, Biochemistry, or related fields.
Prior experience in ADC conjugation is preferred.
Ability to independently conduct experiments in strict accordance with SOPs, prepare standardized experimental reports, and design exploratory experiments (e.g., conjugation condition optimization, novel Payload screening) under guidance, with strong data analysis skills.